Oklahoma County Sheriff's deputies will be conducting sobriety checkpoints from 10 p.m. Saturday to 3 a.m. Sunday in Oklahoma County.
Officials said there will be no tolerance for anyone found driving under the influence of alcohol or drugs. In addition, deputies will be patrolling the county to look for people driving under the influence.
According to the Sheriff's Office, there were six fatal crashes, with four of those deaths from an alcohol-related crash, during the 2010 Thanksgiving Holiday.
Officials advise drivers to not drink and drive, and always wear your seatbelts.