In January, the Cowgirls ended OU's 17-game Bedlam winning streak in front of a packed house in Stillwater.
Over the public address system, Kurt Budke then declared Andrea Riley the best player in the Big 12 after her 45 points performance.
Saturday, the rematch took place in front of a packed house in Norman.
With a final score of 81-71, the Sooners are now in 3rd place in the Big 12, one game ahead of the Cowgirls.
Sherri Coale said the difference Saturday was Amanda Thompson.