Rickie Fowler and Kevin Tway tied for the individual top spot at four-under.
OU placed at fifth, 25-shots back.
The Women's Big 12 Championships were also help Friday at Karsten Creek in Stillwater.
The Cowgirls built a lead after the first day with a 12-shot lead over second place Texas A&M.
OU ranked ninth at the end of day one in Stillwater.